ADAM-rWBC rWBCADAM-rWBC rWBC计数器

 

The ADAM-rWBC uses microscopic cell counting method with a disposable plastic chip for counting residual white blood cells in platelet and red blood cell packs for transfusion.
Leucoreduction of blood products by filtration requires a process control to monitor the amount or residual white blood cells (leucocyte) remaining in the pack.
Accurate determination of residual leucocytes in blood components is high clinical importance.

To date, several labor-intensive, time-consuming or expensive techniques have been used for this purpose.
New accurate and affordable counting method is needed.

 

Features & Competitiveness

Nageotte haemocytometry	Flow cytometry
» The most widely accepted technique. » Labor-intensive microscopic method. » High variability within and between laboratories. » Acceptable precision (CV) < 25%	» Improved reproveducibility » Higher costs. » Sensitivity limit in the range of, 10 to 100 WBCs per mL
Microscopic cell counter with micro-channel chip : C-Reader
» Automation of direct leukocyte counting method in plastic micro-channel chips » Optimized reagent for staining residual white blood cell » Fast, easy and accurate assay » No washing of glass chamber » Economic test cost rather than flow cytometry

Validation 3

Expected (WBC/μL)	Nageotte Chamber			Flow Cytometry			C-Reader
	Mean±SD	CV	Accuracy	Mean±SD	CV	Accuracy	Mean±SD	CV	Accuracy
712	719.2±41.6	5.8	100	700.4±18.3	2.6	100	734±15.6	2.1	100
71.2	72.3±8.6	12.0	90	71.8±2.9	4.0	100	74.8±2.6	3.5	100
32.1	28.9±3.4	11.9	80	27.7±1.4	5.0	90	31.5±1.4	4.6	100
16.1	13.2±1.9	14.2	50	13.7±0.8	5.7	100	14.8±0.7	4.9	100
7.1	6.1±1.5	24.0	60	6.9±0.2	3.5	100	7.4±0.5	7.3	100
6.4	4.7±1.1	22.6	30	6.7±0.9	13.5	90	6.9±1.0	15.0	90
3.5	2.5±0.8	33.4	30	2.8±0.4	14.6	60	3.2±0.4	12.4	80
0.7	0.3±0.1	40.6	20	0.7±0.1	21.4	80	0.7±0.1	15.6	80