Provides four modes of detection in a multi-mode system with an upgrade option to add FP and HTRF modes at a later time. Your applications, your modes, your choice.

The SpectraMax® M4 Multi-Mode Microplate Reader dual monochromator optics allow the widest range of applications without the need to change filters and delivers single-mode performance in one multi-mode platform with the following detection modes:

 

UV-Visible Absorbance (Abs)

Fluorescence Intensity (FI)

Glow Luminescence (Lumi)

Time-Resolved Fluorescence (TRF)

The SpectraMax M4 Microplate Reader is the standard for UV/visible multi-mode reader absorbance, providing ultrafast, full spectral range detection for cuvettes, 96-, and 384-well microplates.

 

Using the patented PathCheck® Pathlength Measurement Technology, the SpectraMax M4 Microplate Reader transforms each well in a microplate to a fixed optical pathlength cuvette and can eliminate standard curves by allowing the calculation of concentrations directly from the absorbance with a known extinction coefficient, as exemplified with nucleic acid and protein quantitation.

 

For fluorescence intensity and time-resolved fluorescence assays, users can select from top or bottom read modes for improved sensitivity for solution and cell-based assays. Assays can be better optimized by scanning across a range of wavelengths in increments as small as 1 nm. Up to 4 wavelength pairs can be read in one protocol for endpoint and kinetic measurements, allowing for fast setup of FRET and TR-FRET assays.

 

For luminescence, the SpectraMax M4 Microplate Reader utilizes a dedicated luminescence photomultiplier tube (PMT), providing the user the maximum signal and lowest background possible for glow luminescence reporter gene assays.

 

If the needs of the researcher change, the SpectraMax M4 Microplate Reader can be upgraded with more detection options including fluorescence polarization and HTRF certified detection making it equivalent to the SpectraMax M5 Microplate Reader or the SpectraMax M5e Microplate Reader.

 

The SpectraMax M4 Microplate Reader is supplied with SoftMax® Pro Data Acquisition & Analysis Software, Molecular Devices' industry leading all-in-one software. Additionally, the SpectraMax M4 Microplate Reader can be seamlessly integrated with the StakMax® Microplate Handling System through SoftMax Pro Software.